Immune checkpoint inhibitors (ICIs) have shown great promise as immunotherapy for restoring T cell function and reactivating anti-tumor immunity.The US Food and Drug Administration (FDA) approved the first immune Ceiling Light checkpoint inhibitor, ipilimumab, in 2011 for advanced melanoma patients, leading to significant improvements in survival r
In recent years, tremendous progress has been made in understanding the roles of extracellular vesicles (EVs) in cancer.Thanks to advancements in molecular biology, it has been found that the fraction of EVs called exosomes or small EVs (sEVs) modulates the sensitivity of cancer cells to chemotherapeutic agents by delivering molecularly active non-
Recipes of multicomponent mixtures of cereals with proteins of high biological value were developed.In experiments, 35 adult male Wistar rats were used.Prior to the experiment, all animals were fed with powdered milk, grain or grain waste, germinated oats, and comprehensive multivitamin preparations, in addition to the standard balanced diet.Agains